“Genetic factors both related and unrelated to nicotine withdrawal may affect attempts to quit smoking”, say researchers from School of Medicine, Washington University.
Research studies show that those who attempt to quit smoking restart within a week, and also about 90% of them relapse within a year. This research study is aimed at identifying the influence of genetics on one’s efforts to quit smoking.
The researchers studied 4000 twins to evaluate three factors that influence smoking habit: genetics, shared environmental factors and unique environmental factors. The researchers compared sets of identical twins with exactly the same genes and fraternal twins with no genetic similarities.
Shared environmental factors mean the experiences commonly shared - the same parents, the same neighborhood, the same school etc. Unique environmental factors are non-shared experiences.
The research proved that shared environmental factors do not make significant contribution to quit smoking. But unique environmental factors determine a person’s odds of quitting. For example, one who has smokers as friends finds it hard to quit smoking.
In the research study it was found that genetic influences account for 54 percent of failures to quit smoking.
Just because genes influence efforts to quit smoking, it doesn’t mean one cannot make his/her own choices. People can still stop smoking, even if their genetics make it very difficult.
Recently developed drugs are targeted at alleviating some of the discomfort smokers experience during withdrawal. When the genetic picture becomes clearer, genes associated with nicotine withdrawal can be targeted. And, drug therapies can also be matched to individual smokers.
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